Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
betACholine dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (580 aa)    
Predicted Functional Partners:
betB
Betaine aldehyde dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the reversible oxidation of betaine aldehyde to the corresponding acid.
 
 
 0.852
betI
Transcriptional repressor BetI; Repressor involved in choline regulation of the bet genes.
 
 
 0.785
EEB85244.1
TPR-domain containing protein; [R] COG0457 FOG: TPR repeat.
  
 
  0.768
EEB83857.1
Conserved hypothetical protein.
    
  0.738
EEB83348.1
TPR/sulfotransferase domain protein; [R] COG0457 FOG: TPR repeat.
    
  0.738
betC
Choline-sulfatase; [P] COG3119 Arylsulfatase A and related enzymes.
 
  
 0.733
EEB83384.1
Putative reductive dehalogenase subfamily protein; [C] COG1600 Uncharacterized Fe-S protein.
    
 0.707
hpaE
5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase; [C] COG1012 NAD-dependent aldehyde dehydrogenases; Belongs to the aldehyde dehydrogenase family.
   
 
 0.666
EEB85236.1
Dehydrogenase/transketolase family protein; [C] COG1071 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit.
   
 
  0.648
pdhB
Pyruvate dehydrogenase complex, E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 
  0.642
Your Current Organism:
Roseobacter sp. GAI101
NCBI taxonomy Id: 391589
Other names: R. sp. GAI101
Server load: medium (46%) [HD]