Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
uraHHydroxyisourate hydrolase; [R] COG2351 Transthyretin-like protein; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (119 aa)    
Predicted Functional Partners:
EEB83516.1
Polysaccharide deacetylase family protein; [G] COG0726 Predicted xylanase/chitin deacetylase.
 
 0.982
EEB82967.1
Class I monoheme cytochrome c; [S] COG3748 Predicted membrane protein.
 
  
 0.876
allA
[F] COG3194 Ureidoglycolate hydrolase.
 
    0.829
xdhB
Xanthine dehydrogenase, molybdopterin binding subunit; [C] COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs.
 
  
 0.804
msrQ
Hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the [...]
   
    0.792
xdhC
[O] COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family.
 
     0.790
xdhA
[C] COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs.
 
     0.787
guaD
Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family.
 
   
 0.775
EEB83714.1
[G] COG0726 Predicted xylanase/chitin deacetylase.
 
 
  0.765
EEB83161.1
Putative allantoin catabolism protein; [R] COG3257 Uncharacterized protein, possibly involved in glyoxylate utilization.
 
   
 0.733
Your Current Organism:
Roseobacter sp. GAI101
NCBI taxonomy Id: 391589
Other names: R. sp. GAI101
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