node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEI92506.1 | pyrD | RLO149_c004780 | RLO149_c004770 | Hypothetical protein DUF952. | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.869 |
AEI94748.1 | carA | RLO149_c027860 | RLO149_c010590 | pyrC': dihydroorotase-like protein. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.820 |
AEI94748.1 | carB | RLO149_c027860 | RLO149_c026920 | pyrC': dihydroorotase-like protein. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.813 |
AEI94748.1 | guaB | RLO149_c027860 | RLO149_c018370 | pyrC': dihydroorotase-like protein. | Inosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.486 |
AEI94748.1 | pyrB | RLO149_c027860 | RLO149_c027840 | pyrC': dihydroorotase-like protein. | Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
AEI94748.1 | pyrC | RLO149_c027860 | RLO149_c024560 | pyrC': dihydroorotase-like protein. | Dihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.917 |
AEI94748.1 | pyrD | RLO149_c027860 | RLO149_c004770 | pyrC': dihydroorotase-like protein. | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.969 |
AEI94748.1 | pyrE | RLO149_c027860 | RLO149_c024570 | pyrC': dihydroorotase-like protein. | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.739 |
AEI94748.1 | pyrF | RLO149_c027860 | RLO149_c038260 | pyrC': dihydroorotase-like protein. | Orotidine 5'-phosphate decarboxylase PyrF. | 0.769 |
carA | AEI94748.1 | RLO149_c010590 | RLO149_c027860 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | pyrC': dihydroorotase-like protein. | 0.820 |
carA | carB | RLO149_c010590 | RLO149_c026920 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | 0.999 |
carA | guaB | RLO149_c010590 | RLO149_c018370 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Inosine-5'-monophosphate dehydrogenase GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.612 |
carA | pheT | RLO149_c010590 | RLO149_c002190 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | phenylalanyl-tRNA synthetase beta chain; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.514 |
carA | pyrB | RLO149_c010590 | RLO149_c027840 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.999 |
carA | pyrC | RLO149_c010590 | RLO149_c024560 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotase PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. | 0.631 |
carA | pyrD | RLO149_c010590 | RLO149_c004770 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Dihydroorotate dehydrogenase PyrD; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.897 |
carA | pyrE | RLO149_c010590 | RLO149_c024570 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotate phosphoribosyltransferase PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.906 |
carA | pyrF | RLO149_c010590 | RLO149_c038260 | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | Orotidine 5'-phosphate decarboxylase PyrF. | 0.894 |
carB | AEI94748.1 | RLO149_c026920 | RLO149_c027860 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | pyrC': dihydroorotase-like protein. | 0.813 |
carB | carA | RLO149_c026920 | RLO149_c010590 | Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. | Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. | 0.999 |