node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AEI95338.1 | cobB | RLO149_c033970 | RLO149_c006260 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.920 |
AEI95338.1 | cobD | RLO149_c033970 | RLO149_c034540 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.920 |
AEI95338.1 | cobL | RLO149_c033970 | RLO149_c006230 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | precorrin-6Y C(5,15)-methyltransferase (decarboxylating). | 0.765 |
AEI95338.1 | cobO | RLO149_c033970 | RLO149_c013150 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | cob(I)yrinic acid a,c-diamide adenosyltransferase CobO; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.944 |
AEI95338.1 | cobP | RLO149_c033970 | RLO149_c035830 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Bifunctional adenosylcobalamin biosynthesis protein CobP; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.925 |
AEI95338.1 | cobQ | RLO149_c033970 | RLO149_c013140 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.922 |
AEI95338.1 | cobS | RLO149_c033970 | RLO149_c028940 | cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.927 |
cobB | AEI95338.1 | RLO149_c006260 | RLO149_c033970 | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.920 |
cobB | cobD | RLO149_c006260 | RLO149_c034540 | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.876 |
cobB | cobJ | RLO149_c006260 | RLO149_c006210 | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-3B C(17)-methyltransferase CobJ. | 0.906 |
cobB | cobL | RLO149_c006260 | RLO149_c006230 | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | precorrin-6Y C(5,15)-methyltransferase (decarboxylating). | 0.990 |
cobB | cobM | RLO149_c006260 | RLO149_c006250 | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Precorrin-4 C(11)-methyltransferase CobM; Belongs to the precorrin methyltransferase family. | 0.986 |
cobB | cobO | RLO149_c006260 | RLO149_c013150 | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | cob(I)yrinic acid a,c-diamide adenosyltransferase CobO; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. | 0.975 |
cobB | cobP | RLO149_c006260 | RLO149_c035830 | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Bifunctional adenosylcobalamin biosynthesis protein CobP; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. | 0.895 |
cobB | cobQ | RLO149_c006260 | RLO149_c013140 | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.959 |
cobB | cobS | RLO149_c006260 | RLO149_c028940 | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Cobalamin-5-phosphate synthase CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.804 |
cobB | cobT | RLO149_c006260 | RLO149_c028930 | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase CobT; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.916 |
cobD | AEI95338.1 | RLO149_c034540 | RLO149_c033970 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | cob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.920 |
cobD | cobB | RLO149_c034540 | RLO149_c006260 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | Cobyrinic acid A,C-diamide synthase CobB; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.876 |
cobD | cobJ | RLO149_c034540 | RLO149_c006210 | Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | precorrin-3B C(17)-methyltransferase CobJ. | 0.814 |