STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEI95197.1Putative threo-3-hydroxyaspartate ammonia-lyase. (324 aa)    
Predicted Functional Partners:
ilvH
Putative acetolactate synthase small subunit IlvH.
  
 
 0.950
thrC
Threonine synthase ThrC.
  
 
 0.940
leuB1
Isopropylmalate dehydrogenase LeuB; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.
 
 
 0.933
leuB2
Isopropylmalate dehydrogenase LeuB.
 
 
 0.933
AEI94994.1
Putative acetolacetate synthase, catabolic; Belongs to the TPP enzyme family.
 
 0.931
ilvI
Acetolactate synthase isozyme 3 large subunit IlvI.
 
 0.930
ilvG
Acetolactate synthase IlvG; Belongs to the TPP enzyme family.
 
 0.928
AEI92530.1
Putative serine/threonine dehydratase.
  
  
 
0.928
ilvA
Threonine dehydratase biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
  
 
0.926
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
  
 0.923
Your Current Organism:
Roseobacter litoralis
NCBI taxonomy Id: 391595
Other names: R. litoralis Och 149, Roseobacter litoralis Och 149, Roseobacter litoralis str. Och 149, Roseobacter litoralis strain Och 149
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