STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yedYSulfoxide reductase catalytic subunit YedY; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to re [...] (301 aa)    
Predicted Functional Partners:
yedZ
Sulfoxide reductase heme-binding subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalyti [...]
 
  
 0.995
soxD4
Sulfite oxidase cytochrome subunit SoxD.
  
 
 0.903
AEI95545.1
Putative Rieske (2Fe-2S) protein; Containing a ferric reductase like transmembrane component.
  
  
 0.677
AEI95728.1
Putative haloacid dehalogenase-like hydrolase.
       0.506
AEI95243.1
Putative HIUase/transthyretin family protein.
  
   0.499
soxE
Flavocytochrome c cytochrome subunit SoxE.
  
 
 0.456
msrA1
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.420
uraH
Hydroxyisourate hydrolase UraH; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
   
   0.420
msrA2
Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.420
moaE
Molybdopterin-converting factor subunit MoaE.
 
   
 0.410
Your Current Organism:
Roseobacter litoralis
NCBI taxonomy Id: 391595
Other names: R. litoralis Och 149, Roseobacter litoralis Och 149, Roseobacter litoralis str. Och 149, Roseobacter litoralis strain Och 149
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.