STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM82334.1AMP-dependent synthetase and ligase; COG1022 Long-chain acyl-CoA synthetases (AMP-forming). (559 aa)    
Predicted Functional Partners:
rplE
50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.
    
 
 0.845
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
    
  0.790
EDM83019.1
Acyltransferase family protein; COG0477 Permeases of the major facilitator superfamily.
   
 0.776
EDM84058.1
Ankyrin; COG0666 FOG: Ankyrin repeat.
  
 0.704
EDM83588.1
Short chain dehydrogenase; COG3320 Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes.
   
 0.695
EDM82953.1
Two-component hybrid sensor and regulator; COG0642 Signal transduction histidine kinase.
    
  0.689
EDM82371.1
Sensor histidine kinase; COG0477 Permeases of the major facilitator superfamily.
    
  0.673
EDM82689.1
PAS; COG0642 Signal transduction histidine kinase.
    
  0.666
EDM82810.1
Two component sensor kinase/response regulator hybrid; COG0642 Signal transduction histidine kinase.
    
  0.659
EDM84593.1
COG0642 Signal transduction histidine kinase.
    
  0.656
Your Current Organism:
Limnobacter sp. MED105
NCBI taxonomy Id: 391597
Other names: L. sp. MED105
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.