node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDM84374.1 | guaA | LMED105_02388 | LMED105_14213 | Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.426 |
EDM84374.1 | tatA | LMED105_02388 | LMED105_06282 | Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Twin argininte translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.555 |
EDM84374.1 | tatB | LMED105_02388 | LMED105_06287 | Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Twin-arginine translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.584 |
EDM84374.1 | tatC | LMED105_02388 | LMED105_06292 | Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Putative Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.499 |
EDM85134.1 | hisA | LMED105_06277 | LMED105_06257 | HIT (Histidine triad) family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | 0.688 |
EDM85134.1 | hisE | LMED105_06277 | LMED105_06272 | HIT (Histidine triad) family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | COG0140 Phosphoribosyl-ATP pyrophosphohydrolase. | 0.737 |
EDM85134.1 | hisF | LMED105_06277 | LMED105_06262 | HIT (Histidine triad) family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.688 |
EDM85134.1 | hisI | LMED105_06277 | LMED105_06267 | HIT (Histidine triad) family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.712 |
EDM85134.1 | tatA | LMED105_06277 | LMED105_06282 | HIT (Histidine triad) family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Twin argininte translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.740 |
EDM85134.1 | tatB | LMED105_06277 | LMED105_06287 | HIT (Histidine triad) family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Twin-arginine translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.680 |
EDM85134.1 | tatC | LMED105_06277 | LMED105_06292 | HIT (Histidine triad) family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | Putative Sec-independent protein translocase protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.613 |
fliL | tatA | LMED105_11075 | LMED105_06282 | Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. | Twin argininte translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.750 |
fliL | tatB | LMED105_11075 | LMED105_06287 | Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family. | Twin-arginine translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.627 |
guaA | EDM84374.1 | LMED105_14213 | LMED105_02388 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.426 |
guaA | hisA | LMED105_14213 | LMED105_06257 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | 0.940 |
guaA | hisF | LMED105_14213 | LMED105_06262 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Imidazoleglycerol phosphate synthase, cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.648 |
guaA | tatA | LMED105_14213 | LMED105_06282 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Twin argininte translocase protein A; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.981 |
guaA | tatB | LMED105_14213 | LMED105_06287 | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | Twin-arginine translocation protein TatB; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation. | 0.981 |
hisA | EDM85134.1 | LMED105_06257 | LMED105_06277 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | HIT (Histidine triad) family protein; COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases. | 0.688 |
hisA | guaA | LMED105_06257 | LMED105_14213 | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; COG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase. | Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP. | 0.940 |