node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDM82038.1 | EDM82626.1 | LMED105_06648 | LMED105_07718 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.812 |
EDM82038.1 | EDM83056.1 | LMED105_06648 | LMED105_12240 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.689 |
EDM82038.1 | EDM83209.1 | LMED105_06648 | LMED105_09860 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 3-demethylubiquinone-9 3-methyltransferase-like protein; COG0500 SAM-dependent methyltransferases. | 0.554 |
EDM82038.1 | glyA | LMED105_06648 | LMED105_16178 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.455 |
EDM82038.1 | mnmC | LMED105_06648 | LMED105_03972 | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 5-methylaminomethyl-2-thiouridine methyltransferase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.444 |
EDM82566.1 | EDM83209.1 | LMED105_07418 | LMED105_09860 | Methylase/methyltransferase; COG0500 SAM-dependent methyltransferases. | 3-demethylubiquinone-9 3-methyltransferase-like protein; COG0500 SAM-dependent methyltransferases. | 0.794 |
EDM82566.1 | metH | LMED105_07418 | LMED105_03550 | Methylase/methyltransferase; COG0500 SAM-dependent methyltransferases. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.550 |
EDM82626.1 | EDM82038.1 | LMED105_07718 | LMED105_06648 | Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.812 |
EDM82626.1 | EDM83056.1 | LMED105_07718 | LMED105_12240 | Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 0.639 |
EDM82626.1 | EDM83209.1 | LMED105_07718 | LMED105_09860 | Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 3-demethylubiquinone-9 3-methyltransferase-like protein; COG0500 SAM-dependent methyltransferases. | 0.554 |
EDM82626.1 | glyA | LMED105_07718 | LMED105_16178 | Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.455 |
EDM82626.1 | mnmC | LMED105_07718 | LMED105_03972 | Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 5-methylaminomethyl-2-thiouridine methyltransferase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.454 |
EDM83056.1 | EDM82038.1 | LMED105_12240 | LMED105_06648 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.689 |
EDM83056.1 | EDM82626.1 | LMED105_12240 | LMED105_07718 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.639 |
EDM83056.1 | EDM83209.1 | LMED105_12240 | LMED105_09860 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 3-demethylubiquinone-9 3-methyltransferase-like protein; COG0500 SAM-dependent methyltransferases. | 0.497 |
EDM83056.1 | EDM84000.1 | LMED105_12240 | LMED105_13528 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | Putative RTX toxin. | 0.457 |
EDM83056.1 | mnmC | LMED105_12240 | LMED105_03972 | Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. | 5-methylaminomethyl-2-thiouridine methyltransferase; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the C-terminal section; belongs to the DAO family. | 0.604 |
EDM83209.1 | EDM82038.1 | LMED105_09860 | LMED105_06648 | 3-demethylubiquinone-9 3-methyltransferase-like protein; COG0500 SAM-dependent methyltransferases. | Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.554 |
EDM83209.1 | EDM82566.1 | LMED105_09860 | LMED105_07418 | 3-demethylubiquinone-9 3-methyltransferase-like protein; COG0500 SAM-dependent methyltransferases. | Methylase/methyltransferase; COG0500 SAM-dependent methyltransferases. | 0.794 |
EDM83209.1 | EDM82626.1 | LMED105_09860 | LMED105_07718 | 3-demethylubiquinone-9 3-methyltransferase-like protein; COG0500 SAM-dependent methyltransferases. | Hypothetical protein; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.554 |