STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC106757639Nicastrin. (669 aa)    
Predicted Functional Partners:
LOC106780688
Probable gamma-secretase subunit PEN-2.
    
 0.999
LOC106753789
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
  
 0.994
LOC106765558
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
  
 0.994
LOC106776165
Gamma-secretase subunit APH1-like.
   
 0.990
LOC106756184
U-box domain-containing protein 33-like isoform X1.
   
 
  0.604
LOC106759539
U-box domain-containing protein 33.
   
 
  0.604
LOC106771949
Exocyst complex component SEC5; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family.
   
  
 0.596
LOC106759410
C-terminal binding protein AN.
    
 
 0.468
LOC106762090
Golgin candidate 5.
      
 0.449
LOC106760741
Signal peptide peptidase.
      
 0.441
Your Current Organism:
Vigna radiata
NCBI taxonomy Id: 3916
Other names: Phaseolus aureus, Phaseolus aureus Roxb., Phaseolus radiatus, Phaseolus radiatus L., V. radiata var. radiata, Vigna radiata var. radiata, golden gram, green gram, mung bean
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.