STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP71081.1COG0389 Nucleotidyltransferase/DNA polymerase involved in DNA repair. (418 aa)    
Predicted Functional Partners:
EDP71172.1
Putative UmuD/RumA DNA repair protein; COG1974 SOS-response transcriptional repressors (RecA-mediated autopeptidases); Belongs to the peptidase S24 family.
 
 
 0.921
EDP70114.1
DNA polymerase III, beta-subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 0.899
EDP70932.1
Hypothetical protein; COG3298 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB.
   
 0.803
EDP72770.1
Pyruvate flavodoxin dehydrogenase.
   
   0.793
EDP71316.1
Hypothetical protein; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases.
   
 0.789
EDP71216.1
COG2176 DNA polymerase III, alpha subunit (gram-positive type).
  
  
 0.670
EDP71217.1
COG0587 DNA polymerase III, alpha subunit.
  
  
 0.670
recA
DNA recombination protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.663
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.662
EDP71511.1
Hypothetical protein; COG0076 Glutamate decarboxylase and related PLP-dependent proteins.
    
   0.609
Your Current Organism:
Flavobacteriales bacterium ALC1
NCBI taxonomy Id: 391603
Other names: F. bacterium ALC-1, Flavobacteriales bacterium ALC-1
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