STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folE-2GTP cyclohydrolase I. (224 aa)    
Predicted Functional Partners:
EDP71635.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.919
EDP72395.1
Deoxyguanosine kinase/deoxyadenosine kinase subunit; COG0801 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase.
  
 0.815
EDP69506.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.786
EDP72866.1
COG1539 Dihydroneopterin aldolase.
 
 
 0.786
EDP70180.1
Hypothetical protein.
       0.773
EDP70176.1
Hypothetical protein.
       0.768
EDP70177.1
Hypothetical protein.
       0.768
EDP70178.1
Hypothetical protein; COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component.
       0.768
EDP69895.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.759
EDP70175.1
COG1131 ABC-type multidrug transport system, ATPase component.
       0.751
Your Current Organism:
Flavobacteriales bacterium ALC1
NCBI taxonomy Id: 391603
Other names: F. bacterium ALC-1, Flavobacteriales bacterium ALC-1
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.