Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
EDY85723.1[O] COG1333 ResB protein required for cytochrome c biosynthesis. (646 aa)    
Predicted Functional Partners:
EDY85733.1
Cytochrome c assembly protein; [R] COG4137 ABC-type uncharacterized transport system, permease component.
 
  
 0.988
EDY86593.1
[S] COG2968 Uncharacterized conserved protein.
  
     0.599
EDY85732.1
Dsba oxidoreductase; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
       0.554
EDY86218.1
Redoxin domain protein; [OC] COG0526 Thiol-disulfide isomerase and thioredoxins.
  
    0.531
EDY85773.1
[C] COG2863 Cytochrome c553.
       0.518
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
    0.501
EDY86182.1
Hypothetical protein; [R] COG1058 Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; molybdopterin binding domain.
  
     0.483
EDY85664.1
Conserved hypothetical protein; [S] COG3308 Predicted membrane protein.
  
     0.482
engB
GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.
       0.430
Your Current Organism:
gamma proteobacterium HTCC5015
NCBI taxonomy Id: 391615
Other names: g. proteobacterium HTCC5015
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