Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
EDY86092.1Peptidase S16, lon domain protein; [R] COG2802 Uncharacterized protein, similar to the N-terminal domain of Lon protease. (215 aa)    
Predicted Functional Partners:
groL
Chaperonin GroL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
    
  0.753
htpG
Heat shock protein HtpG; Molecular chaperone. Has ATPase activity.
     
  0.734
kdkA
3-deoxy-D-manno-octulosonic acid kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.
  
 
  0.616
hepA
RNA polymerase-associated protein HepA; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily.
    
  0.577
EDY86403.1
Conserved hypothetical protein; [IQ] COG0236 Acyl carrier protein.
    
  0.569
EDY86037.1
Patatin; [R] COG1752 Predicted esterase of the alpha-beta hydrolase superfamily.
       0.560
EDY87279.1
Putative tetratricopeptide repeat family protein; [K] COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit.
  
  
  0.519
gspL
General secretion pathway protein L; Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.
  
     0.477
EDY85559.1
Hypothetical protein; [R] COG0457 FOG: TPR repeat.
   
 
  0.450
EDY85322.1
Conserved hypothetical protein.
    
  0.445
Your Current Organism:
gamma proteobacterium HTCC5015
NCBI taxonomy Id: 391615
Other names: g. proteobacterium HTCC5015
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