STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mdhMalate dehydrogenase Mdh; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)    
Predicted Functional Partners:
gltA
Citrate synthase GltA; Belongs to the citrate synthase family.
  
 0.992
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.971
dme
NAD-dependent malic enzyme Dme.
  
 0.965
maeB
NADP-dependent malic enzyme MaeB.
  
 0.965
tyrB
Aromatic-amino-acid aminotransferase TyrB.
   
 0.948
pyc
Pyruvate carboxylase Pyc; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.948
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
 
 
 0.946
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.944
AGI70844.1
Putative malate/L-lactate dehydrogenase; Belongs to the LDH2/MDH2 oxidoreductase family.
    
 0.928
AGI70671.1
Putative citrate lyase subunit beta; Belongs to the HpcH/HpaI aldolase family.
  
 
 0.927
Your Current Organism:
Octadecabacter arcticus
NCBI taxonomy Id: 391616
Other names: O. arcticus 238, Octadecabacter arcticus 238, Octadecabacter arcticus CIP 106732, Octadecabacter arcticus str. 238, Octadecabacter arcticus strain 238
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