STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folK2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase FolK. (189 aa)    
Predicted Functional Partners:
folP
Dihydropteroate synthase FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.998
AFO90383.1
Dihydroneopterin aldolase-like protein.
 
 
 0.993
AFO93120.1
Putative tRNA-nucleotidyltransferase; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.758
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
 
  
 0.752
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
       0.721
AFO89844.1
Hypothetical protein.
       0.717
folC
Putative bifunctional enzyme FolC; Includes folylpolyglutamate synthase and dihydrofolate synthase; Belongs to the folylpolyglutamate synthase family.
 
  
 0.709
ispDF
Bifunctional enzyme IspDF; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
  
  
 0.685
spoT
Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
       0.673
AFO89848.1
Hypothetical protein.
       0.642
Your Current Organism:
Phaeobacter inhibens
NCBI taxonomy Id: 391619
Other names: P. inhibens DSM 17395, Phaeobacter gallaeciensis DSM 17395, Phaeobacter inhibens DSM 17395
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