STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
gcvHGlycine cleavage system protein GcvH; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (120 aa)    
Predicted Functional Partners:
lpdA3
Dihydrolipoyl dehydrogenase LpdA.
 
 0.995
lpd2
Dihydrolipoyl dehydrogenase 2.
 
  
 0.983
lpdA2
Dihydrolipoyl dehydrogenase LpdA.
 
  
 0.978
glyA
Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
 
 
 0.961
AFO92143.1
Putative serine hydroxymethyltransferase.
 
 
 0.950
AFO92079.1
Putative serine-glyoxylate aminotransferase.
  
 
 0.918
AFO92023.1
Putative sarcosine dehydrogenase; Belongs to the GcvT family.
 
 0.901
gltB
Glutamate synthase [NADPH] large chain.
   
 
 0.893
AFO92014.1
Putative sarcosine dehydrogenase; Belongs to the GcvT family.
 
 0.892
lipA
Lipoyl synthase LipA; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
 
 
 0.888
Your Current Organism:
Phaeobacter inhibens
NCBI taxonomy Id: 391619
Other names: P. inhibens DSM 17395, Phaeobacter gallaeciensis DSM 17395, Phaeobacter inhibens DSM 17395
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