node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFO90586.1 | thiC | PGA1_c08590 | PGA1_c09110 | Heme NO binding domain-containing protein. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.895 |
AFO90586.1 | thiD | PGA1_c08590 | PGA1_c09030 | Heme NO binding domain-containing protein. | Phosphomethylpyrimidine kinase ThiD. | 0.538 |
AFO90586.1 | thiE | PGA1_c08590 | PGA1_c09050 | Heme NO binding domain-containing protein. | Thiamine-phosphate pyrophosphorylase ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.772 |
AFO90586.1 | thiG | PGA1_c08590 | PGA1_c09070 | Heme NO binding domain-containing protein. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.921 |
AFO90586.1 | thiS | PGA1_c08590 | PGA1_c09090 | Heme NO binding domain-containing protein. | Thiamine biosynthesis protein ThiS. | 0.835 |
AFO92554.1 | thiG | PGA1_c28970 | PGA1_c09070 | Putative FAD dependent oxidoreductase. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.937 |
AFO92554.1 | thiO | PGA1_c28970 | PGA1_c09100 | Putative FAD dependent oxidoreductase. | Putative thiamine biosynthesis oxidoreductase ThiO. | 0.906 |
dxs | thiD | PGA1_c34170 | PGA1_c09030 | 1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Phosphomethylpyrimidine kinase ThiD. | 0.414 |
dxs | thiG | PGA1_c34170 | PGA1_c09070 | 1-deoxy-D-xylulose-5-phosphate synthase Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.931 |
moeB | thiC | PGA1_c26620 | PGA1_c09110 | Putative molybdopterin biosynthesis protein MoeB. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.714 |
moeB | thiD | PGA1_c26620 | PGA1_c09030 | Putative molybdopterin biosynthesis protein MoeB. | Phosphomethylpyrimidine kinase ThiD. | 0.671 |
moeB | thiE | PGA1_c26620 | PGA1_c09050 | Putative molybdopterin biosynthesis protein MoeB. | Thiamine-phosphate pyrophosphorylase ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.746 |
moeB | thiG | PGA1_c26620 | PGA1_c09070 | Putative molybdopterin biosynthesis protein MoeB. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.875 |
moeB | thiS | PGA1_c26620 | PGA1_c09090 | Putative molybdopterin biosynthesis protein MoeB. | Thiamine biosynthesis protein ThiS. | 0.735 |
thiC | AFO90586.1 | PGA1_c09110 | PGA1_c08590 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Heme NO binding domain-containing protein. | 0.895 |
thiC | moeB | PGA1_c09110 | PGA1_c26620 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Putative molybdopterin biosynthesis protein MoeB. | 0.714 |
thiC | thiD | PGA1_c09110 | PGA1_c09030 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Phosphomethylpyrimidine kinase ThiD. | 0.998 |
thiC | thiE | PGA1_c09110 | PGA1_c09050 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Thiamine-phosphate pyrophosphorylase ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). | 0.993 |
thiC | thiF | PGA1_c09110 | PGA1_c09040 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Putative adenylyltransferase ThiF. | 0.868 |
thiC | thiG | PGA1_c09110 | PGA1_c09070 | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | Thiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.995 |