node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFO91291.1 | gmk | PGA1_c15840 | PGA1_c15830 | Hypothetical protein. | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | 0.950 |
AFO91291.1 | rpoZ | PGA1_c15840 | PGA1_c01000 | Hypothetical protein. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.529 |
apt | gmk | PGA1_c06370 | PGA1_c15830 | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | 0.966 |
apt | gpt | PGA1_c06370 | PGA1_c16830 | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Xanthine phosphoribosyltransferase Gpt; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.926 |
apt | guaA | PGA1_c06370 | PGA1_c14610 | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.994 |
apt | hpt | PGA1_c06370 | PGA1_c14710 | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Hypoxanthine-guanine phosphoribosyltransferase Hpt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.941 |
apt | ndk | PGA1_c06370 | PGA1_c19750 | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.404 |
apt | surE | PGA1_c06370 | PGA1_c10770 | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.921 |
gmk | AFO91291.1 | PGA1_c15830 | PGA1_c15840 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | Hypothetical protein. | 0.950 |
gmk | apt | PGA1_c15830 | PGA1_c06370 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.966 |
gmk | gpt | PGA1_c15830 | PGA1_c16830 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | Xanthine phosphoribosyltransferase Gpt; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | 0.918 |
gmk | guaA | PGA1_c15830 | PGA1_c14610 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.971 |
gmk | hpt | PGA1_c15830 | PGA1_c14710 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | Hypoxanthine-guanine phosphoribosyltransferase Hpt; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.955 |
gmk | ndk | PGA1_c15830 | PGA1_c19750 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | Nucleoside diphosphate kinase Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.934 |
gmk | pykA | PGA1_c15830 | PGA1_c06970 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | Pyruvate kinase PykA; Belongs to the pyruvate kinase family. | 0.921 |
gmk | rpoZ | PGA1_c15830 | PGA1_c01000 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.915 |
gmk | spoT | PGA1_c15830 | PGA1_c01010 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase SpoT; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.932 |
gmk | surE | PGA1_c15830 | PGA1_c10770 | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | 5'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.915 |
gpt | apt | PGA1_c16830 | PGA1_c06370 | Xanthine phosphoribosyltransferase Gpt; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Adenine phosphoribosyltransferase Apt; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.926 |
gpt | gmk | PGA1_c16830 | PGA1_c15830 | Xanthine phosphoribosyltransferase Gpt; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. | Guanylate kinase Gmk; Essential for recycling GMP and indirectly, cGMP. | 0.918 |