STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hemA5-aminolevulinate synthase HemA. (409 aa)    
Predicted Functional Partners:
soxA1
Sarcosine oxidase subunit alpha; Belongs to the GcvT family.
  
 0.929
soxA3
Sarcosine oxidase subunit alpha; Belongs to the GcvT family.
  
 0.929
kbl
2-amino-3-ketobutyrate coenzyme A ligase Kbl; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
  
  
 
0.920
hemB
Delta-aminolevulinic acid dehydratase HemB; Belongs to the ALAD family.
    
 0.911
glyA
Serine hydroxymethyltransferase GlyA; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.910
AFO92143.1
Putative serine hydroxymethyltransferase.
  
 
 0.910
AFO92079.1
Putative serine-glyoxylate aminotransferase.
    
 0.909
fabD
Malonyl CoA-acyl carrier protein transacylase FabD.
 
 
 0.908
ltaE
Low specificity L-threonine aldolase LtaE; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde.
    
 0.908
soxB3
Sarcosine oxidase subunit beta.
  
 
 0.904
Your Current Organism:
Phaeobacter inhibens
NCBI taxonomy Id: 391619
Other names: P. inhibens DSM 17395, Phaeobacter gallaeciensis DSM 17395, Phaeobacter inhibens DSM 17395
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