node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFO90700.1 | clpA | PGA1_c09810 | PGA1_c25150 | Hypothetical protein. | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.631 |
AFO90700.1 | clpB | PGA1_c09810 | PGA1_c32440 | Hypothetical protein. | Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.631 |
AFO90700.1 | dnaK | PGA1_c09810 | PGA1_c34530 | Hypothetical protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.943 |
AFO90700.1 | groL | PGA1_c09810 | PGA1_c24920 | Hypothetical protein. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.754 |
AFO90700.1 | groS | PGA1_c09810 | PGA1_c24930 | Hypothetical protein. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.562 |
AFO90700.1 | grpE | PGA1_c09810 | PGA1_c35010 | Hypothetical protein. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.824 |
AFO90700.1 | hrcA | PGA1_c09810 | PGA1_c35020 | Hypothetical protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.684 |
AFO91152.1 | dnaK | PGA1_c14390 | PGA1_c34530 | Hypothetical protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.897 |
AFO92749.1 | clpA | PGA1_c31010 | PGA1_c25150 | dnaJ domain-containing protein. | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | 0.631 |
AFO92749.1 | clpB | PGA1_c31010 | PGA1_c32440 | dnaJ domain-containing protein. | Chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. | 0.631 |
AFO92749.1 | dnaK | PGA1_c31010 | PGA1_c34530 | dnaJ domain-containing protein. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.915 |
AFO92749.1 | groL | PGA1_c31010 | PGA1_c24920 | dnaJ domain-containing protein. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.754 |
AFO92749.1 | groS | PGA1_c31010 | PGA1_c24930 | dnaJ domain-containing protein. | Chaperonin GroS; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. | 0.553 |
AFO92749.1 | grpE | PGA1_c31010 | PGA1_c35010 | dnaJ domain-containing protein. | Protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.803 |
AFO92749.1 | hrcA | PGA1_c31010 | PGA1_c35020 | dnaJ domain-containing protein. | Heat-inducible transcription repressor HrcA; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.652 |
clpA | AFO90700.1 | PGA1_c25150 | PGA1_c09810 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | Hypothetical protein. | 0.631 |
clpA | AFO92749.1 | PGA1_c25150 | PGA1_c31010 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | dnaJ domain-containing protein. | 0.631 |
clpA | dnaJ | PGA1_c25150 | PGA1_c34540 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.680 |
clpA | dnaK | PGA1_c25150 | PGA1_c34530 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.915 |
clpA | groL | PGA1_c25150 | PGA1_c24920 | ATP-dependent Clp protease ATP-binding subunit; Belongs to the ClpA/ClpB family. | 60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.605 |