STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDQ05229.1Periplasmic serine protease, DO/DeqQ family protein; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family. (494 aa)    
Predicted Functional Partners:
EDQ06852.1
COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain; Belongs to the peptidase S1C family.
  
  
 
0.896
EDQ02974.1
COG0554 Glycerol kinase; Belongs to the FGGY kinase family.
   
 0.860
EDQ03675.1
Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
 0.815
EDQ04110.1
Protease ecfE, putative; COG0750 Predicted membrane-associated Zn-dependent proteases 1.
 
  
 0.745
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 
  0.690
EDQ05226.1
HflK protein; HflC and HflK could encode or regulate a protease.
 
 
 0.679
EDQ05227.1
HflC protein, putative; HflC and HflK could regulate a protease.
 
 
 0.675
secY
Protein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
  
 0.647
EDQ03581.1
GAF sensor hybrid histidine kinase; COG0642 Signal transduction histidine kinase.
 
  
 0.642
EDQ06449.1
Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases.
    
 0.601
Your Current Organism:
Sulfitobacter indolifex
NCBI taxonomy Id: 391624
Other names: Oceanibulbus indolifex HEL-45, S. indolifex HEL-45, Sulfitobacter indolifex HEL-45
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.