node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EDQ04181.1 | EDQ04869.1 | OIHEL45_14669 | OIHEL45_14250 | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.992 |
EDQ04181.1 | EDQ05121.1 | OIHEL45_14669 | OIHEL45_10278 | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.772 |
EDQ04181.1 | EDQ05267.1 | OIHEL45_14669 | OIHEL45_11008 | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.944 |
EDQ04181.1 | EDQ05815.1 | OIHEL45_14669 | OIHEL45_03355 | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Oxidoreductase, putative; COG0277 FAD/FMN-containing dehydrogenases. | 0.906 |
EDQ04181.1 | EDQ06058.1 | OIHEL45_14669 | OIHEL45_04570 | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.943 |
EDQ04181.1 | EDQ06327.1 | OIHEL45_14669 | OIHEL45_05915 | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | COG0281 Malic enzyme. | 0.993 |
EDQ04181.1 | EDQ06491.1 | OIHEL45_14669 | OIHEL45_06735 | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.944 |
EDQ04181.1 | leuA | OIHEL45_14669 | OIHEL45_03815 | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.893 |
EDQ04181.1 | mdh | OIHEL45_14669 | OIHEL45_01755 | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.955 |
EDQ04181.1 | pckA | OIHEL45_14669 | OIHEL45_04125 | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.984 |
EDQ04869.1 | EDQ04181.1 | OIHEL45_14250 | OIHEL45_14669 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.992 |
EDQ04869.1 | EDQ05121.1 | OIHEL45_14250 | OIHEL45_10278 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | 0.895 |
EDQ04869.1 | EDQ05267.1 | OIHEL45_14250 | OIHEL45_11008 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.930 |
EDQ04869.1 | EDQ06058.1 | OIHEL45_14250 | OIHEL45_04570 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | COG0469 Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.429 |
EDQ04869.1 | EDQ06327.1 | OIHEL45_14250 | OIHEL45_05915 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | COG0281 Malic enzyme. | 0.917 |
EDQ04869.1 | EDQ06491.1 | OIHEL45_14250 | OIHEL45_06735 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | Glutamate synthase, large subunit; COG0067 Glutamate synthase domain 1. | 0.954 |
EDQ04869.1 | leuA | OIHEL45_14250 | OIHEL45_03815 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.588 |
EDQ04869.1 | mdh | OIHEL45_14250 | OIHEL45_01755 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.997 |
EDQ04869.1 | pckA | OIHEL45_14250 | OIHEL45_04125 | COG0372 Citrate synthase; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. | 0.912 |
EDQ05121.1 | EDQ04181.1 | OIHEL45_10278 | OIHEL45_14669 | COG1884 Methylmalonyl-CoA mutase, N-terminal domain/subunit. | Pyruvate dehydrogenase subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.772 |