STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDM77052.1Sua5/YciO/YrdC/YwlC; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (356 aa)    
Predicted Functional Partners:
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.712
tsaD
Metalloendopeptidase, putative, glycoprotease family protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 
 0.605
EDM76298.1
Putative glycoprotein endopeptidase; COG1214 Inactive homolog of metal-dependent proteases, putative molecular chaperone.
    
 0.580
EDM75441.1
Hypothetical protein; COG0802 Predicted ATPase or kinase.
    
 0.580
EDM77051.1
Hypothetical protein; COG2368 Aromatic ring hydroxylase.
       0.570
EDM77050.1
Hypothetical protein.
       0.562
EDM74303.1
Hypothetical protein; COG0127 Xanthosine triphosphate pyrophosphatase.
  
  
 0.511
rpoZ
DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
    0.469
EDM74423.1
Hypothetical protein; COG2384 Predicted SAM-dependent methyltransferase.
  
     0.455
EDM81224.1
Ribosomal RNA small subunit methyltransferase B; COG0144 tRNA and rRNA cytosine-C5-methylases; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
  
 0.440
Your Current Organism:
Plesiocystis pacifica
NCBI taxonomy Id: 391625
Other names: P. pacifica SIR-1, Plesiocystis pacifica SIR-1, Plesiocystis pacifica str. SIR-1, Plesiocystis pacifica strain SIR-1
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