node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AGI66832.1 | dmgdh1 | OAN307_c11300 | OAN307_c24060 | Sarcosine oxidase subunit alpha family protein; Belongs to the GcvT family. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.825 |
AGI66832.1 | dmgdh2 | OAN307_c11300 | OAN307_c42890 | Sarcosine oxidase subunit alpha family protein; Belongs to the GcvT family. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.815 |
AGI66832.1 | dmgdh3 | OAN307_c11300 | OAN307_c24050 | Sarcosine oxidase subunit alpha family protein; Belongs to the GcvT family. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.828 |
AGI66832.1 | gcvH | OAN307_c11300 | OAN307_c42330 | Sarcosine oxidase subunit alpha family protein; Belongs to the GcvT family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.851 |
AGI66832.1 | gcvP | OAN307_c11300 | OAN307_c42320 | Sarcosine oxidase subunit alpha family protein; Belongs to the GcvT family. | Glycine dehydrogenase GcvP; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.987 |
AGI66832.1 | glyA1 | OAN307_c11300 | OAN307_c37120 | Sarcosine oxidase subunit alpha family protein; Belongs to the GcvT family. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.740 |
AGI66832.1 | sardh1 | OAN307_c11300 | OAN307_c46300 | Sarcosine oxidase subunit alpha family protein; Belongs to the GcvT family. | Sarcosine dehydrogenase; Belongs to the GcvT family. | 0.808 |
AGI66832.1 | sardh2 | OAN307_c11300 | OAN307_c43050 | Sarcosine oxidase subunit alpha family protein; Belongs to the GcvT family. | Sarcosine dehydrogenase; Belongs to the GcvT family. | 0.815 |
dmgdh1 | AGI66832.1 | OAN307_c24060 | OAN307_c11300 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase subunit alpha family protein; Belongs to the GcvT family. | 0.825 |
dmgdh1 | dmgdh2 | OAN307_c24060 | OAN307_c42890 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.759 |
dmgdh1 | dmgdh3 | OAN307_c24060 | OAN307_c24050 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.871 |
dmgdh1 | gcvH | OAN307_c24060 | OAN307_c42330 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.884 |
dmgdh1 | gcvP | OAN307_c24060 | OAN307_c42320 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Glycine dehydrogenase GcvP; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.985 |
dmgdh1 | glyA1 | OAN307_c24060 | OAN307_c37120 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.611 |
dmgdh1 | sardh1 | OAN307_c24060 | OAN307_c46300 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine dehydrogenase; Belongs to the GcvT family. | 0.768 |
dmgdh1 | sardh2 | OAN307_c24060 | OAN307_c43050 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine dehydrogenase; Belongs to the GcvT family. | 0.769 |
dmgdh1 | soxA2 | OAN307_c24060 | OAN307_c32990 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase subunit alpha; Belongs to the GcvT family. | 0.932 |
dmgdh2 | AGI66832.1 | OAN307_c42890 | OAN307_c11300 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Sarcosine oxidase subunit alpha family protein; Belongs to the GcvT family. | 0.815 |
dmgdh2 | dmgdh1 | OAN307_c42890 | OAN307_c24060 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.759 |
dmgdh2 | dmgdh3 | OAN307_c42890 | OAN307_c24050 | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | Dimethylglycine dehydrogenase; Belongs to the GcvT family. | 0.760 |