Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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textmining
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experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Veis_0807Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)); Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: pol:Bpro_1421 malate dehydrogenase (oxaloacetate decarboxylating) (NADP+), phosphate acetyltransferase. (768 aa)    
Predicted Functional Partners:
mdh
Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.979
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 
 0.974
Veis_0196
PFAM: pyruvate kinase; KEGG: pol:Bpro_4634 pyruvate kinase; Belongs to the pyruvate kinase family.
  
 0.967
fumC
Fumarase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.966
fumC-2
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.966
Veis_3214
Fumarase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
 
 
 0.964
Veis_1646
PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: rfr:Rfer_0093 malate dehydrogenase (oxaloacetate decarboxylating) (NADP+).
 
 
0.954
Veis_1917
TIGRFAM: dihydrolipoamide dehydrogenase; PFAM: biotin/lipoyl attachment domain-containing protein; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: rfr:Rfer_2214 dihydrolipoamide dehydrogenase.
  
 
 0.953
Veis_1919
2-oxo-acid dehydrogenase E1 subunit, homodimeric type; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.952
Veis_3057
Fumarase alpha subunit; TIGRFAM: hydro-lyases, Fe-S type, tartrate/fumarate subfamily, alpha subunit; PFAM: Fe-S type hydro-lyases tartrate/fumarate alpha region; KEGG: rha:RHA1_ro08824 fumarate hydratase, class I.
  
 
 0.945
Your Current Organism:
Verminephrobacter eiseniae
NCBI taxonomy Id: 391735
Other names: V. eiseniae EF01-2, Verminephrobacter eiseniae EF01-2, Verminephrobacter eiseniae str. EF01-2, Verminephrobacter eiseniae strain EF01-2
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