STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
S7S_10250COG3139 Uncharacterized protein conserved in bacteria. (96 aa)    
Predicted Functional Partners:
msrB
methionine-R-sulfoxide reductase; COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family.
  
    0.947
pepN
COG0308 Aminopeptidase N.
       0.834
msrA-2
Peptide methionine sulfoxide reductase family protein; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
    0.815
nadK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
 
     0.783
S7S_07985
Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
    0.742
S7S_08820
COG3318 Predicted metal-binding protein related to the C-terminal domain of SecA; Belongs to the UPF0149 family.
  
     0.718
S7S_12055
COG2825 Outer membrane protein.
  
     0.713
S7S_02350
COG3151 Uncharacterized protein conserved in bacteria.
  
     0.682
topA
DNA topoisomerase I subunit omega; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus rem [...]
  
     0.662
S7S_04630
COG3105 Uncharacterized protein conserved in bacteria.
  
     0.656
Your Current Organism:
Alcanivorax pacificus
NCBI taxonomy Id: 391936
Other names: A. pacificus W11-5, Alcanivorax pacificus W11-5, Alcanivorax sp. W11-5
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.