node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
S7S_08760 | S7S_08770 | S7S_08760 | S7S_08770 | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | Nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.992 |
S7S_08760 | S7S_08775 | S7S_08760 | S7S_08775 | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | Precorrin-2 dehydrogenase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.914 |
S7S_08760 | S7S_08785 | S7S_08760 | S7S_08785 | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | 0.937 |
S7S_08760 | S7S_11265 | S7S_08760 | S7S_11265 | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | FAD-dependent oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | 0.729 |
S7S_08760 | cysG | S7S_08760 | S7S_08990 | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.635 |
S7S_08770 | S7S_08760 | S7S_08770 | S7S_08760 | Nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | 0.992 |
S7S_08770 | S7S_08775 | S7S_08770 | S7S_08775 | Nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | Precorrin-2 dehydrogenase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.904 |
S7S_08770 | S7S_08785 | S7S_08770 | S7S_08785 | Nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | 0.977 |
S7S_08770 | S7S_11265 | S7S_08770 | S7S_11265 | Nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | FAD-dependent oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | 0.958 |
S7S_08770 | cysG | S7S_08770 | S7S_08990 | Nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.540 |
S7S_08775 | S7S_08760 | S7S_08775 | S7S_08760 | Precorrin-2 dehydrogenase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | 0.914 |
S7S_08775 | S7S_08770 | S7S_08775 | S7S_08770 | Precorrin-2 dehydrogenase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | Nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.904 |
S7S_08775 | S7S_08785 | S7S_08775 | S7S_08785 | Precorrin-2 dehydrogenase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | 0.762 |
S7S_08775 | S7S_11265 | S7S_08775 | S7S_11265 | Precorrin-2 dehydrogenase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | FAD-dependent oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | 0.618 |
S7S_08775 | S7S_13330 | S7S_08775 | S7S_13330 | Precorrin-2 dehydrogenase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | 0.635 |
S7S_08775 | cysG | S7S_08775 | S7S_08990 | Precorrin-2 dehydrogenase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. | 0.991 |
S7S_08785 | S7S_08760 | S7S_08785 | S7S_08760 | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | 0.937 |
S7S_08785 | S7S_08770 | S7S_08785 | S7S_08770 | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | Nitrate reductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. NasA/NapA/NarB subfamily. | 0.977 |
S7S_08785 | S7S_08775 | S7S_08785 | S7S_08775 | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | Precorrin-2 dehydrogenase; COG0007 Uroporphyrinogen-III methylase; Belongs to the precorrin methyltransferase family. | 0.762 |
S7S_08785 | S7S_11265 | S7S_08785 | S7S_11265 | COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases. | FAD-dependent oxidoreductase; COG0446 Uncharacterized NAD(FAD)-dependent dehydrogenases. | 0.620 |