| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NA2_00935 | NA2_00940 | NA2_00935 | NA2_00940 | COG3288 NAD/NADP transhydrogenase alpha subunit. | Pyridine nucleotide transhydrogenase alpha subunit-like protein; COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.941 |
| NA2_00935 | NA2_00945 | NA2_00935 | NA2_00945 | COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
| NA2_00935 | NA2_01385 | NA2_00935 | NA2_01385 | COG3288 NAD/NADP transhydrogenase alpha subunit. | COG0686 Alanine dehydrogenase; Belongs to the AlaDH/PNT family. | 0.556 |
| NA2_00935 | NA2_16842 | NA2_00935 | NA2_16842 | COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |
| NA2_00935 | NA2_16847 | NA2_00935 | NA2_16847 | COG3288 NAD/NADP transhydrogenase alpha subunit. | COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.990 |
| NA2_00935 | ilvC | NA2_00935 | NA2_00735 | COG3288 NAD/NADP transhydrogenase alpha subunit. | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.495 |
| NA2_00935 | nadD | NA2_00935 | NA2_11325 | COG3288 NAD/NADP transhydrogenase alpha subunit. | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.539 |
| NA2_00935 | nadE-2 | NA2_00935 | NA2_15759 | COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.644 |
| NA2_00935 | ppnK | NA2_00935 | NA2_18725 | COG3288 NAD/NADP transhydrogenase alpha subunit. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.782 |
| NA2_00935 | rpoC | NA2_00935 | NA2_20799 | COG3288 NAD/NADP transhydrogenase alpha subunit. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.555 |
| NA2_00940 | NA2_00935 | NA2_00940 | NA2_00935 | Pyridine nucleotide transhydrogenase alpha subunit-like protein; COG3288 NAD/NADP transhydrogenase alpha subunit. | COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.941 |
| NA2_00940 | NA2_00945 | NA2_00940 | NA2_00945 | Pyridine nucleotide transhydrogenase alpha subunit-like protein; COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.998 |
| NA2_00940 | NA2_01385 | NA2_00940 | NA2_01385 | Pyridine nucleotide transhydrogenase alpha subunit-like protein; COG3288 NAD/NADP transhydrogenase alpha subunit. | COG0686 Alanine dehydrogenase; Belongs to the AlaDH/PNT family. | 0.485 |
| NA2_00940 | NA2_16842 | NA2_00940 | NA2_16842 | Pyridine nucleotide transhydrogenase alpha subunit-like protein; COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.992 |
| NA2_00940 | nadD | NA2_00940 | NA2_11325 | Pyridine nucleotide transhydrogenase alpha subunit-like protein; COG3288 NAD/NADP transhydrogenase alpha subunit. | Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.539 |
| NA2_00940 | nadE-2 | NA2_00940 | NA2_15759 | Pyridine nucleotide transhydrogenase alpha subunit-like protein; COG3288 NAD/NADP transhydrogenase alpha subunit. | NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.644 |
| NA2_00940 | ppnK | NA2_00940 | NA2_18725 | Pyridine nucleotide transhydrogenase alpha subunit-like protein; COG3288 NAD/NADP transhydrogenase alpha subunit. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.786 |
| NA2_00940 | rpoC | NA2_00940 | NA2_20799 | Pyridine nucleotide transhydrogenase alpha subunit-like protein; COG3288 NAD/NADP transhydrogenase alpha subunit. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.522 |
| NA2_00945 | NA2_00935 | NA2_00945 | NA2_00935 | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.999 |
| NA2_00945 | NA2_00940 | NA2_00945 | NA2_00940 | NAD(P)(+) transhydrogenase; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Pyridine nucleotide transhydrogenase alpha subunit-like protein; COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.998 |