STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NA2_01475Maleylacetoacetate isomerase; COG0625 Glutathione S-transferase. (215 aa)    
Predicted Functional Partners:
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
 
 0.947
NA2_01480
Fumarylpyruvate hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
  
 
 0.929
NA2_01470
COG3435 Gentisate 1,2-dioxygenase.
 
  
 0.904
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.871
NA2_01465
Hypothetical protein; COG1482 Phosphomannose isomerase.
    
  0.868
rpoD
RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.
    
   0.863
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.832
NA2_16992
COG3185 4-hydroxyphenylpyruvate dioxygenase and related hemolysins.
 
  
 0.796
NA2_01485
TRAP transporter, 4TM/12TM fusion protein; COG4666 TRAP-type uncharacterized transport system, fused permease components.
       0.773
NA2_17012
Fumarylacetoacetate (FAA) hydrolase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway).
 
 
 0.760
Your Current Organism:
Nitratireductor pacificus
NCBI taxonomy Id: 391937
Other names: N. pacificus pht-3B, Nitratireductor pacificus pht-3B, Nitratireductor sp. pht-3B
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