node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NA2_08616 | NA2_12109 | NA2_08616 | NA2_12109 | 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; COG3971 2-keto-4-pentenoate hydratase. | 5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.446 |
NA2_12099 | NA2_12104 | NA2_12099 | NA2_12104 | Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily. | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.633 |
NA2_12099 | NA2_12109 | NA2_12099 | NA2_12109 | Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily. | 5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.587 |
NA2_12104 | NA2_12099 | NA2_12104 | NA2_12099 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily. | 0.633 |
NA2_12104 | NA2_12109 | NA2_12104 | NA2_12109 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.754 |
NA2_12104 | NA2_12114 | NA2_12104 | NA2_12114 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.706 |
NA2_12109 | NA2_08616 | NA2_12109 | NA2_08616 | 5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 2-oxo-hepta-3-ene-1,7-dioic acid hydratase; COG3971 2-keto-4-pentenoate hydratase. | 0.446 |
NA2_12109 | NA2_12099 | NA2_12109 | NA2_12099 | 5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | Mandelate racemase/muconate lactonizing protein; COG4948 L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily. | 0.587 |
NA2_12109 | NA2_12104 | NA2_12109 | NA2_12104 | 5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.754 |
NA2_12109 | NA2_12114 | NA2_12109 | NA2_12114 | 5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 0.565 |
NA2_12109 | hmgA | NA2_12109 | NA2_17022 | 5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 0.571 |
NA2_12114 | NA2_12104 | NA2_12114 | NA2_12104 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases); Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.706 |
NA2_12114 | NA2_12109 | NA2_12114 | NA2_12109 | Short-chain dehydrogenase/reductase SDR; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). | 5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.565 |
hmgA | NA2_12109 | NA2_17022 | NA2_12109 | Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate. | 5-carboxymethyl-2-hydroxymuconate delta-isomerase; COG0179 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway). | 0.571 |