STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NA2_13280COG3852 Signal transduction histidine kinase, nitrogen specific. (380 aa)    
Predicted Functional Partners:
ntrC
Fis family two component sigma-54 specific transcriptional regulator; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 0.991
NA2_17147
Sensor histidine kinase; COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains.
 
0.964
NA2_13430
COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
  
 0.962
NA2_10058
COG0347 Nitrogen regulatory protein PII; Belongs to the P(II) protein family.
  
 0.955
NA2_02389
COG0642 Signal transduction histidine kinase.
  
 
 0.877
NA2_21003
Multi-sensor hybrid histidine kinase / cell cycle control histidine kinase CckA; COG0642 Signal transduction histidine kinase.
 
 
0.877
NA2_04766
Two-component sensor/response regulator hybrid; COG0642 Signal transduction histidine kinase.
 
 
0.873
NA2_17222
Periplasmic sensor hybrid histidine kinase; COG0591 Na+/proline symporter.
  
 0.870
NA2_10873
COG0642 Signal transduction histidine kinase.
 
 
0.868
NA2_11455
PAS sensor protein; COG0642 Signal transduction histidine kinase.
 
 
0.867
Your Current Organism:
Nitratireductor pacificus
NCBI taxonomy Id: 391937
Other names: N. pacificus pht-3B, Nitratireductor pacificus pht-3B, Nitratireductor sp. pht-3B
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