| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NA2_00115 | NA2_07979 | NA2_00115 | NA2_07979 | Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases. | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | 0.588 |
| NA2_00115 | NA2_10923 | NA2_00115 | NA2_10923 | Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.672 |
| NA2_00115 | NA2_13932 | NA2_00115 | NA2_13932 | Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases. | Lyase; COG2513 PEP phosphonomutase and related enzymes. | 0.771 |
| NA2_00115 | NA2_14157 | NA2_00115 | NA2_14157 | Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases. | COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. | 0.600 |
| NA2_00115 | NA2_14312 | NA2_00115 | NA2_14312 | Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases. | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.764 |
| NA2_00115 | glcB | NA2_00115 | NA2_08039 | Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.781 |
| NA2_00115 | gltA | NA2_00115 | NA2_06507 | Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases. | COG0372 Citrate synthase; Belongs to the citrate synthase family. | 0.908 |
| NA2_00115 | mdh | NA2_00115 | NA2_10728 | Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.408 |
| NA2_07979 | NA2_00115 | NA2_07979 | NA2_00115 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.588 |
| NA2_07979 | NA2_10923 | NA2_07979 | NA2_10923 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.681 |
| NA2_07979 | NA2_12274 | NA2_07979 | NA2_12274 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.619 |
| NA2_07979 | NA2_13932 | NA2_07979 | NA2_13932 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Lyase; COG2513 PEP phosphonomutase and related enzymes. | 0.743 |
| NA2_07979 | NA2_14157 | NA2_07979 | NA2_14157 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | COG0075 Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase. | 0.790 |
| NA2_07979 | glcB | NA2_07979 | NA2_08039 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.769 |
| NA2_07979 | mdh | NA2_07979 | NA2_10728 | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.712 |
| NA2_10923 | NA2_00115 | NA2_10923 | NA2_00115 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Bifunctional aldehyde dehydrogenase/enoyl-CoA hydratase; COG1012 NAD-dependent aldehyde dehydrogenases. | 0.672 |
| NA2_10923 | NA2_07979 | NA2_10923 | NA2_07979 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | COG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases. | 0.681 |
| NA2_10923 | NA2_12274 | NA2_10923 | NA2_12274 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | 0.428 |
| NA2_10923 | NA2_13932 | NA2_10923 | NA2_13932 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Lyase; COG2513 PEP phosphonomutase and related enzymes. | 0.750 |
| NA2_10923 | NA2_14312 | NA2_10923 | NA2_14312 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.805 |