STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source; Belongs to the NAD synthetase family. (325 aa)    
Predicted Functional Partners:
NA2_14022
COG0236 Acyl carrier protein.
 
     0.949
NA2_14017
COG0367 Asparagine synthase (glutamine-hydrolyzing).
 
   
 0.862
NA2_14027
Putative long-chain fatty-acid-CoA ligase protein; COG0318 Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II.
 
     0.816
nadD
Nicotinic acid mononucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.741
ppnK
Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.694
NA2_16268
Isochorismatase hydrolase; COG1335 Amidases related to nicotinamidase.
  
  
 0.693
nadE-2
NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
0.631
NA2_17871
NUDIX hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family.
    
 0.629
NA2_16842
NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.622
NA2_08364
NUDIX hydrolase; COG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding.
  
 
  0.610
Your Current Organism:
Nitratireductor pacificus
NCBI taxonomy Id: 391937
Other names: N. pacificus pht-3B, Nitratireductor pacificus pht-3B, Nitratireductor sp. pht-3B
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