node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFU34083.1 | SFU34721.1 | SAMN05421543_101189 | SAMN05421543_101216 | DNA polymerase-1. | Tryptophan RNA-binding attenuator protein inhibitory protein. | 0.496 |
SFU34083.1 | SFU62132.1 | SAMN05421543_101189 | SAMN05421543_1057 | DNA polymerase-1. | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | 0.997 |
SFU34083.1 | SFU95916.1 | SAMN05421543_101189 | SAMN05421543_11582 | DNA polymerase-1. | DNA polymerase III, beta subunit. | 0.996 |
SFU34083.1 | SFV01074.1 | SAMN05421543_101189 | SAMN05421543_11938 | DNA polymerase-1. | ATP-dependent DNA helicase DinG. | 0.981 |
SFU34083.1 | rnhA | SAMN05421543_101189 | SAMN05421543_11363 | DNA polymerase-1. | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.911 |
SFU34083.1 | rnhB | SAMN05421543_101189 | SAMN05421543_10716 | DNA polymerase-1. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.711 |
SFU34083.1 | thyA | SAMN05421543_101189 | SAMN05421543_102239 | DNA polymerase-1. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.666 |
SFU34721.1 | SFU34083.1 | SAMN05421543_101216 | SAMN05421543_101189 | Tryptophan RNA-binding attenuator protein inhibitory protein. | DNA polymerase-1. | 0.496 |
SFU34721.1 | SFU74742.1 | SAMN05421543_101216 | SAMN05421543_10715 | Tryptophan RNA-binding attenuator protein inhibitory protein. | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | 0.809 |
SFU34721.1 | nuoI | SAMN05421543_101216 | SAMN05421543_105149 | Tryptophan RNA-binding attenuator protein inhibitory protein. | NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. | 0.792 |
SFU34721.1 | rnhB | SAMN05421543_101216 | SAMN05421543_10716 | Tryptophan RNA-binding attenuator protein inhibitory protein. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.686 |
SFU46554.1 | rnhB | SAMN05421543_102152 | SAMN05421543_10716 | Signal peptidase I; Belongs to the peptidase S26 family. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.734 |
SFU62132.1 | SFU34083.1 | SAMN05421543_1057 | SAMN05421543_101189 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA polymerase-1. | 0.997 |
SFU62132.1 | SFU95916.1 | SAMN05421543_1057 | SAMN05421543_11582 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | DNA polymerase III, beta subunit. | 0.530 |
SFU62132.1 | SFV01074.1 | SAMN05421543_1057 | SAMN05421543_11938 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | ATP-dependent DNA helicase DinG. | 0.847 |
SFU62132.1 | rnhA | SAMN05421543_1057 | SAMN05421543_11363 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.592 |
SFU62132.1 | rnhB | SAMN05421543_1057 | SAMN05421543_10716 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.933 |
SFU62132.1 | thyA | SAMN05421543_1057 | SAMN05421543_102239 | DNA polymerase-3 subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of re [...] | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.732 |
SFU74742.1 | SFU34721.1 | SAMN05421543_10715 | SAMN05421543_101216 | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | Tryptophan RNA-binding attenuator protein inhibitory protein. | 0.809 |
SFU74742.1 | rnhB | SAMN05421543_10715 | SAMN05421543_10716 | Ribosome biogenesis GTPase A; Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity; Belongs to the TRAFAC class YlqF/YawG GTPase family. MTG1 subfamily. | RNase HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.759 |