node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDL35068.1 | SDL35109.1 | SAMN05660860_00407 | SAMN05660860_00408 | RecQ zinc-binding. | ATP-dependent DNA helicase, RecQ family. | 0.980 |
SDL35068.1 | SDL41162.1 | SAMN05660860_00407 | SAMN05660860_00564 | RecQ zinc-binding. | ATP-dependent DNA helicase RecQ. | 0.763 |
SDL35068.1 | SDL72463.1 | SAMN05660860_00407 | SAMN05660860_01122 | RecQ zinc-binding. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.909 |
SDL35068.1 | SDM42570.1 | SAMN05660860_00407 | SAMN05660860_02482 | RecQ zinc-binding. | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.922 |
SDL35068.1 | SDM49092.1 | SAMN05660860_00407 | SAMN05660860_02654 | RecQ zinc-binding. | ATP-dependent DNA helicase PcrA. | 0.922 |
SDL35068.1 | mutL | SAMN05660860_00407 | SAMN05660860_00860 | RecQ zinc-binding. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.918 |
SDL35068.1 | recA | SAMN05660860_00407 | SAMN05660860_00109 | RecQ zinc-binding. | Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.977 |
SDL35068.1 | topA | SAMN05660860_00407 | SAMN05660860_00086 | RecQ zinc-binding. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.989 |
SDL35109.1 | SDL35068.1 | SAMN05660860_00408 | SAMN05660860_00407 | ATP-dependent DNA helicase, RecQ family. | RecQ zinc-binding. | 0.980 |
SDL35109.1 | SDL72463.1 | SAMN05660860_00408 | SAMN05660860_01122 | ATP-dependent DNA helicase, RecQ family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.909 |
SDL35109.1 | SDM42570.1 | SAMN05660860_00408 | SAMN05660860_02482 | ATP-dependent DNA helicase, RecQ family. | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.936 |
SDL35109.1 | SDM49092.1 | SAMN05660860_00408 | SAMN05660860_02654 | ATP-dependent DNA helicase, RecQ family. | ATP-dependent DNA helicase PcrA. | 0.932 |
SDL35109.1 | mutL | SAMN05660860_00408 | SAMN05660860_00860 | ATP-dependent DNA helicase, RecQ family. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.922 |
SDL35109.1 | recA | SAMN05660860_00408 | SAMN05660860_00109 | ATP-dependent DNA helicase, RecQ family. | Recombination protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.978 |
SDL35109.1 | topA | SAMN05660860_00408 | SAMN05660860_00086 | ATP-dependent DNA helicase, RecQ family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.989 |
SDL41162.1 | SDL35068.1 | SAMN05660860_00564 | SAMN05660860_00407 | ATP-dependent DNA helicase RecQ. | RecQ zinc-binding. | 0.763 |
SDL41162.1 | SDL72463.1 | SAMN05660860_00564 | SAMN05660860_01122 | ATP-dependent DNA helicase RecQ. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.909 |
SDL41162.1 | SDM42570.1 | SAMN05660860_00564 | SAMN05660860_02482 | ATP-dependent DNA helicase RecQ. | DNA helicase-2 / ATP-dependent DNA helicase PcrA. | 0.927 |
SDL41162.1 | SDM49092.1 | SAMN05660860_00564 | SAMN05660860_02654 | ATP-dependent DNA helicase RecQ. | ATP-dependent DNA helicase PcrA. | 0.926 |
SDL41162.1 | mutL | SAMN05660860_00564 | SAMN05660860_00860 | ATP-dependent DNA helicase RecQ. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.922 |