Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SET81702.1Cell division control protein 6; Involved in regulation of DNA replication. (409 aa)    
Predicted Functional Partners:
SET72591.1
Replicative DNA helicase Mcm.
  
 0.849
SET28136.1
Putative nucleotide binding protein.
  
     0.691
SET46030.1
GTP-binding conserved hypothetical protein TIGR00650.
  
   
 0.676
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
   
 0.666
SET17725.1
GTP-binding conserved hypothetical protein TIGR00650.
  
   
 0.651
priL
DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair.
  
 
 0.643
SET27855.1
Hypothetical protein; Involved in DNA damage repair.
  
     0.642
SET81727.1
Dihydropteroate synthase.
       0.623
SET22419.1
Uncharacterized protein.
  
     0.622
nac
Nascent polypeptide associated complex NAC; Contacts the emerging nascent chain on the ribosome. Belongs to the NAC-alpha family.
  
     0.595
Your Current Organism:
Haloterrigena hispanica
NCBI taxonomy Id: 392421
Other names: DSM 18328, H. hispanica, Haloterrigena hispanica Romano et al. 2007, Haloterrigena sp. FP1, strain FP1
Server load: low (18%) [HD]