Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pilHTwitching motility protein PilH. (121 aa)    
Predicted Functional Partners:
pilJ
Type IV pilus biogenesis protein PilJ.
 
  0.977
LP43_2118
Hypothetical protein.
 
0.973
cheA
Signal transduction histidine kinase CheA.
 
0.972
pilI
Type IV pili signal transduction protein PilI.
 
 
  0.971
LP43_2231
Hypothetical protein.
 
0.970
LP43_1567
Hypothetical protein.
 
 0.969
LP43_2119
Hypothetical protein.
 
0.956
LP43_2228
Hypothetical protein.
 
0.950
LP43_0722
Hypothetical protein.
 
 0.944
LP43_2129
Sensory box histidine kinase/response regulator.
 
0.939
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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