Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
co-expression
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gene co-occurrence
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[Homology]
Score
LP43_0052Formaldehyde activating enzyme. (172 aa)    
Predicted Functional Partners:
mch
N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase; Catalyzes the hydrolysis of methenyl-H(4)MPT(+) to 5-formyl- H(4)MPT; Belongs to the MCH family.
 
   
 0.983
LP43_0506
Methylene tetrahydromethanopterin dehydrogenase.
 
  
 0.967
ffsA
Formylmethanofuran--tetrahydromethanopterin N-formyltransferase; Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT); Belongs to the FTR family.
 
  
 0.964
LP43_0508
Methylene tetrahydromethanopterin dehydrogenase.
  
  
 0.961
LP43_0051
Triphosphoribosyl-dephospho-CoA synthetase.
 
     0.902
LP43_1262
Formaldehyde activating enzyme.
  
  
 
0.876
mxaA
MxaA protein.
  
  
  0.868
mxaI
Methanol dehydrogenase, small subunit.
  
  
  0.861
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.852
mxaL-2
MxaL protein.
  
  
  0.846
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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