LP43_0067 protein (Methylophaga thiooxydans)

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LP43_0067

Multimodular transpeptidase-transglycosylase. (736 aa)

Predicted Functional Partners:

ftsI

0.971

mrdA

0.968

LP43_0457

0.907

mtgA

0.893

LP43_1039

0.883

LP43_2236

0.879

LP43_1880

0.870

murA

0.674

nagZ

0.639

rodA

0.627

Your Current Organism:

Methylophaga thiooxydans

NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LP43_0067	LP43_0457	LP43_0067	LP43_0457	Multimodular transpeptidase-transglycosylase.	Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.907
LP43_0067	LP43_1039	LP43_0067	LP43_1039	Multimodular transpeptidase-transglycosylase.	D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.	0.883
LP43_0067	LP43_1880	LP43_0067	LP43_1880	Multimodular transpeptidase-transglycosylase.	LppC putative lipoprotein.	0.870
LP43_0067	LP43_2236	LP43_0067	LP43_2236	Multimodular transpeptidase-transglycosylase.	D-alanyl-D-alanine carboxypeptidase.	0.879
LP43_0067	ftsI	LP43_0067	LP43_1866	Multimodular transpeptidase-transglycosylase.	Cell division protein FtsI [Peptidoglycan synthetase]; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.	0.971
LP43_0067	mrdA	LP43_0067	LP43_1035	Multimodular transpeptidase-transglycosylase.	Penicillin-binding protein 2 (PBP-2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.968
LP43_0067	mtgA	LP43_0067	LP43_2126	Multimodular transpeptidase-transglycosylase.	Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.	0.893
LP43_0067	murA	LP43_0067	LP43_2423	Multimodular transpeptidase-transglycosylase.	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.674
LP43_0067	nagZ	LP43_0067	LP43_1535	Multimodular transpeptidase-transglycosylase.	Beta N-acetyl-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.	0.639
LP43_0067	rodA	LP43_0067	LP43_1036	Multimodular transpeptidase-transglycosylase.	Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.	0.627
LP43_0457	LP43_0067	LP43_0457	LP43_0067	Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Multimodular transpeptidase-transglycosylase.	0.907
LP43_0457	LP43_1039	LP43_0457	LP43_1039	Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.	0.902
LP43_0457	LP43_1880	LP43_0457	LP43_1880	Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	LppC putative lipoprotein.	0.433
LP43_0457	LP43_2236	LP43_0457	LP43_2236	Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	D-alanyl-D-alanine carboxypeptidase.	0.899
LP43_0457	ftsI	LP43_0457	LP43_1866	Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Cell division protein FtsI [Peptidoglycan synthetase]; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.	0.988
LP43_0457	mrdA	LP43_0457	LP43_1035	Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Penicillin-binding protein 2 (PBP-2); Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.974
LP43_0457	mtgA	LP43_0457	LP43_2126	Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family.	0.875
LP43_0457	murA	LP43_0457	LP43_2423	Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.	0.423
LP43_0457	nagZ	LP43_0457	LP43_1535	Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Beta N-acetyl-glucosaminidase; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily.	0.529
LP43_0457	rodA	LP43_0457	LP43_1036	Multimodular transpeptidase-transglycosylase; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.	0.765

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