Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
LP43_0248Hypothetical protein. (343 aa)    
Predicted Functional Partners:
pilQ
Type IV pilus biogenesis protein PilQ.
 
 
 
 0.963
pilO
Type IV pilus biogenesis protein PilO.
  
   0.926
pilN
Type IV pilus biogenesis protein PilN.
  
 
   0.926
LP43_1379
Hypothetical protein.
  
   0.925
pilM
Type IV pilus biogenesis protein PilM.
  
 
   0.924
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP.
    
  0.891
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
  0.885
LP43_0247
Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake.
       0.807
smg
Protein of unknown function Smg; Belongs to the Smg family.
 
     0.781
LP43_2224
Type IV pilus biogenesis protein PilZ.
  
    0.774
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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