Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_0420LSU ribosomal protein L25p. (229 aa)    
Predicted Functional Partners:
rplM
LSU ribosomal protein L13p (L13Ae); This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
 
 0.983
rpsB
SSU ribosomal protein S2p (SAe); Belongs to the universal ribosomal protein uS2 family.
  
 
 0.981
rpsF
SSU ribosomal protein S6p; Binds together with S18 to 16S ribosomal RNA.
  
 
 0.981
rpsO
SSU ribosomal protein S15p (S13e); Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.
   
 0.980
rpsI
SSU ribosomal protein S9p (S16e); Belongs to the universal ribosomal protein uS9 family.
   
 
 0.980
rplU
LSU ribosomal protein L21p; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
  
 
 0.978
rpsD
SSU ribosomal protein S4p (S9e); One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
   
 
 0.978
rplI
LSU ribosomal protein L9p; Binds to the 23S rRNA.
  
 
 0.978
rplK
LSU ribosomal protein L11p (L12e); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.
   
 
 0.977
rplJ
LSU ribosomal protein L10p (P0); Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
   
 
 0.977
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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