Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
pilCType IV fimbrial assembly protein PilC. (415 aa)    
Predicted Functional Partners:
pilB
Type IV fimbrial assembly, ATPase PilB.
 
 
 0.993
LP43_0536
Leader peptidase (Prepilin peptidase)/N-methyltransferase; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
  
 0.989
pilB-2
Type IV fimbrial assembly, ATPase PilB.
 
 
 0.974
pilQ
Type IV pilus biogenesis protein PilQ.
 
 
 
 0.916
pilM
Type IV pilus biogenesis protein PilM.
 
 
 
 0.902
LP43_2411
Twitching motility protein PilT.
 
   
 0.877
pilO
Type IV pilus biogenesis protein PilO.
 
 
 
 0.870
coaE
Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family.
       0.833
pilT
Twitching motility protein PilT.
  
   
 0.826
LP43_2410
Twitching motility protein PilT.
  
   
 0.826
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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