Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LP43_0822Ferric siderophore transport system, periplasmic binding protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family. (219 aa)    
Predicted Functional Partners:
LP43_0821
Biopolymer transport protein ExbD/TolR.
 
 
 0.988
LP43_0819
MotA/TolQ/ExbB proton channel family protein.
 
 
 0.976
LP43_0820
Ferric siderophore transport system, biopolymer transport protein ExbB.
 
 
 0.972
LP43_0823
TPR domain protein, putative component of TonB system.
 
 
   0.951
LP43_0818
TonB system biopolymer transport component/Chromosome segregation ATPase.
 
  
  0.949
LP43_1972
TonB-dependent receptor.
 
 0.878
tolQ
MotA/TolQ/ExbB proton channel family protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
  
 
 0.871
tolR
Tol biopolymer transport system, TolR protein; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity.
 
 
 0.852
exbD-2
Biopolymer transport protein ExbD/TolR.
 
   0.851
LP43_0917
Biopolymer transport protein ExbD/TolR.
  
 
 0.830
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.