Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LP43_0838Formate dehydrogenase-O, major subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (965 aa)    
Predicted Functional Partners:
LP43_0839
Formate dehydrogenase-O, iron-sulfur subunit/putative formate dehydrogenase iron-sulfur subunit.
 
 0.999
LP43_0841
Formate dehydrogenase O gamma subunit.
 
 0.997
LP43_0835
Iron-sulfur cluster-binding protein.
 
 0.994
LP43_0842
Tungsten-containing formate dehydrogenase beta subunit.
 
 
 0.981
LP43_0836
Putative formate dehydrogenase-specific chaperone.
 
 0.956
fdhD
Formate dehydrogenase chain D; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family.
 
 
 0.916
LP43_1870
Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
   
 0.906
mauM
Ferredoxin-type protein NapG/MauM (periplasmic nitrate reductase).
 
 0.900
LP43_0834
Hypothetical protein.
 
     0.868
LP43_0832
Hypothetical protein.
 
     0.862
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.