Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ppnPPutative cytoplasmic protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (104 aa)    
Predicted Functional Partners:
LP43_0259
Uracil phosphoribosyltransferase/Pyrimidine operon regulatory protein PyrR.
     
 0.875
LP43_0490
Decarboxylase family protein.
     
  0.836
LP43_0563
Hypothetical protein; Belongs to the multicopper oxidase YfiH/RL5 family.
     
  0.836
surE
5-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.836
LP43_1694
Hypoxanthine-guanine phosphoribosyltransferase.
     
  0.836
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.836
LP43_2202
5'-nucleotidase.
     
  0.836
LP43_1093
Hypothetical protein.
       0.757
LP43_0240
Glutamate synthase [NADPH] subunit beta.
     
  0.697
LP43_1243
Isoquinoline 1-oxidoreductase alpha subunit.
     
  0.697
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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