Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LP43_1097ComM-related protein. (501 aa)    
Predicted Functional Partners:
LP43_0880
Protein YhgH.
 
  
 0.905
LP43_0247
Rossmann fold nucleotide-binding protein Smf possibly involved in DNA uptake.
 
 0.855
rep
ATP-dependent DNA helicase Rep; Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction.
 
   
 0.819
LP43_1881
Putative endonuclease; Belongs to the UPF0102 family.
 
  
 0.733
LP43_0919
Putative hydrolase (metallo-beta-lactamase superfamily).
 
  
 0.634
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
  
   
 0.580
LP43_1777
Late competence protein ComEA, DNA receptor.
  
  
 0.555
LP43_1099
YcnI.
       0.516
LP43_1096
Hypothetical protein.
       0.460
flgG
Flagellar basal-body rod protein FlgG; Belongs to the flagella basal body rod proteins family.
   
   0.459
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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