Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_1174Citryl-CoA-Lyase; Belongs to the HpcH/HpaI aldolase family. (293 aa)    
Predicted Functional Partners:
LP43_1173
Mesaconyl-CoA hydratase.
 
 
 0.961
LP43_1177
Citrate lyase beta chain; Belongs to the HpcH/HpaI aldolase family.
 
  
  0.945
LP43_1172
Citrate lyase beta chain; Belongs to the HpcH/HpaI aldolase family.
 
  
  0.935
LP43_1178
Acetyl-coenzyme A synthetase.
  
  0.935
LP43_2532
Fumarate hydratase class I, aerobic; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
 0.844
LP43_1170
2-methylcitrate synthase; Belongs to the citrate synthase family.
    
 0.841
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
    
 0.797
LP43_0824
Putative Ribulose-5-phosphate 4-epimerase.
   
    0.793
LP43_0375
Pyruvate carboxyl transferase subunit B.
  
 
 0.765
LP43_2064
Oxaloacetate decarboxylase alpha chain.
  
 
 0.765
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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