Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LP43_1244Transcriptional regulator, AraC family. (302 aa)    
Predicted Functional Partners:
LP43_0241
Glutamate synthase [NADPH] subunit alpha.
    
 0.855
ribB
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
  0.653
ribB-2
3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
     
  0.653
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.639
LP43_1240
CTP:molybdopterin cytidylyltransferase.
       0.603
LP43_1241
Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family.
       0.603
LP43_1242
Isoquinoline 1-oxidoreductase beta subunit.
       0.603
LP43_1243
Isoquinoline 1-oxidoreductase alpha subunit.
       0.603
LP43_0375
Pyruvate carboxyl transferase subunit B.
     
  0.544
LP43_2064
Oxaloacetate decarboxylase alpha chain.
     
  0.544
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
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