Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LP43_1249Cytochrome c oxidase subunit CcoN; Belongs to the heme-copper respiratory oxidase family. (473 aa)    
Predicted Functional Partners:
ccoO
Cytochrome c oxidase subunit CcoO.
 0.999
ccoP
Cytochrome c oxidase subunit CcoP; C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex.
 
 0.996
LP43_1870
Cytochrome c oxidase polypeptide II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 0.971
LP43_1246
Type cbb3 cytochrome oxidase biogenesis protein CcoG, involved in Cu oxidation.
 
  
 0.968
LP43_0842
Tungsten-containing formate dehydrogenase beta subunit.
   
 
 0.916
LP43_0522
Ubiquinol--cytochrome C oxidoreductase, cytochrome C1 subunit.
    
 0.817
LP43_2375
Hypothetical protein.
  
 
 0.810
LP43_0523
Ubiquinol--cytochrome C reductase, cytochrome B subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
   0.780
LP43_0524
Ubiquinol--cytochrome C reductase iron-sulfur subunit; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.
  
 
 0.776
LP43_1109
Cytochrome c5.
 
  0.756
Your Current Organism:
Methylophaga thiooxydans
NCBI taxonomy Id: 392484
Other names: DSM 22068, M. thiooxydans, Methylophaga thiooxidans, Methylophaga thiooxydans corrig. Boden et al. 2011, VKM B-2586, strain DMS010
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.